Current Trials and Studies

MAMA Study

Mama

The MAMA Study is designed to find out whether it is better for women who have arthritis and are pregnant to stop or to continue taking biologic medications throughout pregnancy.

If you are pregnant or planning a pregnancy, and have arthritis which is being treated with a biologic, please visit the MAMA website for more information, or to register your interest in being involved. 

The MAMA Study is designed to find out whether it is better for women who have arthritis and are pregnant to stop or to continue taking biologic medications throughout pregnancy.

If you are pregnant or planning a pregnancy, and have arthritis which is being treated with a biologic, please visit https://www.npeu.ox.ac.uk/mama/participants for more information, or to register your interest in being involved. 

DAISY - Digital Family Support Study

DAISY

About the DAISY Study:

Researchers are exploring whether a digital parent support program called Stepping Stones Online can help behaviours that challenge in children with a learning disability or developmental delay. This study is called The Digital Family Support study - DAISY.

Stepping Stones Online is an online program for parent carers of a child with a learning disability. It covers:

·         Learning strategies to make everyday life easier

·         Supporting communication and everyday skills for children

·         Positive ways to support behaviours that challenge

·          Building your confidence in parenting

Who Can Take Part?

We are looking for parent carers who:

• Live in England

• Have a child aged 2–11 years with a learning disability or developmental delay

What Participation Involves:

Once parent carers complete the screening process and are eligible for the study, they’ll be asked to provide consent to take part. Parent carers will then be asked to complete a set of questionnaires about themselves and their family. This information is kept securely on a protected database which only members of the research management team can access.

Parent carers will then be randomly put into one of two groups. Half of study participants will be given access to Stepping Stones Online, and the other half will continue with the support they usually receive. This will help the research team measure the effectiveness of Stepping Stones Online. After the study, participants who did not access Stepping Stones Online will be offered access.

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Below you will find all our current trials and studies including downloadable information leaflets.

 

Click on a title to see more about the study.

Pain in Peripheral Nerve Lesions (PiPL)

Who is eligible?

  • Patients who are 18-85 years of age.
  • Patients who have a diagnosis of peripheral neuropathy based on a clinical assessment combined with supportive clinical investigations such as abnormal nerve conduction studies, reduced intraepidermal nerve or abnormal findings on quantitative sensory testing or patients with symptoms highly suggestive of neuropathy.
  • Participant is willing and able to give informed consent for participation in the study.

How do I take part?

You will be contacted by letter if you are eligible to take part.

For more information on this study or for information on other avaiolable studies, please visit Be Part of Research

COBALT - Combining Memantine and Cholinesterase Inhibitors in Lewy Dody Dementia Treatment Trial

The trial will look at the use of a drug called Memantine for treatment of people with Dementia with Lewy Bodies (DLB) and Parkinson’s Disease Dementia (PDD) symptoms.

The aim of the COBALT trial is to find out if Memantine treatment can help improve overall health and functioning for people with DLB or PDD.

Potential participants should be currently taking cholinesterase inhibitors (for example, Donepezil also called Aricept’).

What does taking part involve?

  • If you agree to take part, you will join one of two treatment groups for 12 months:

a placebo (‘dummy’ drug) group

OR

a medication (Memantine) group

  • You will have planned visits and phone calls with the local trial team, who will ask you about your symptoms, how you feel and your trial treatment.
  • A family member or person who knows you well will also be asked to answer questions about your symptoms and about how they are feeling.

For more information and to see if you can take part you can contact one of the local trial team

Dementia.research@oxfordhealth.nhs.uk

Tel: 01865 902694

eDiamond - Invitation Only Study for Eligible People with Type 2 Diabetes.

You will receive an invitation by text or letter for this if you are eligible.  

Monet - Carpal Tunnel Syndrome

Do you have mild or moderate Carpal Tunnel Syndrome?

This study investigates the mechanisms of action of neurodynamic exercises to help clinicians identify which patients with carpal tunnel syndrome may benefit more from this treatment.

We will compare the effect of these exercises with a steroid injection (which is also a recommended treatment for carpal tunnel syndrome), or advice.

You can download the full information sheet here which includes how to take part.

HIPPOCRATES - Adults with psoriasis

HPOS is a study of patients with psoriasis running across Europe.

Led by a research team at University of Oxford and University College Dublin we are aiming to identify patients at risk of developing psoriatic arthritis. This is part of a large research project investigating psoriatic arthritis across Europe which is called HIPPOCRATES.

 

We are interested in any adult with psoriasis.

Up to one-third of patients with psoriasis will develop a related arthritis causing inflammation in the joints and tendons. We want to identify which patients will develop arthritis with the long-term aim of trying to prevent the development of arthritis before it occurs.

You can find out more information including how to register to take part at The HPOS Study · HPOS

 

Join Dementia Research

Join Dementia Research is a nationwide online and telephone service that allows people to register their interest in volunteering for dementia research studies.

People with dementia, their carers, or anyone interested in research can be matched to studies.

Sign up today at: www.joindementiaresearch.nihr.ac.uk or download th efull information leaflet here

Research
Page last reviewed: 02 July 2026
Page created: 21 July 2021